A Prodigious Inventory-Taking
نویسندگان
چکیده
منابع مشابه
EHPnet: Taking Inventory of Toxics
Many cellular systems rely on the ability to interpret spatial heterogeneities in chemoattractant concentration to direct cell migration. The accuracy of this process is limited by stochastic fluctuations in the concentration of the external signal and in the internal signaling components. Here we use information theory to determine the optimal scheme to detect the location of an external chemo...
متن کاملThe Prodigious Pustule
has illustrated beautifully how far such detailed studies can take you, especially if one considers its recent extension to genome-wide searches using microarrays and bioinformatics methods. I also regret that I did not open my mind earlier to questions of cell biology. I could not imagine how someone wanted to work on mutants like stardust, crumbs, bazooka, klarsicht or nullo. They seemed to m...
متن کاملVamsi Mootha: Taking an inventory of mitochondria
Mitochondria, the energy reactors of the cell, are estimated to contain approximately 1,500 proteins, but the mito-chondrial genome itself only encodes about 13 of them. The remaining proteins are immigrants that are encoded by the nuclear genome. Vamsi Mootha is using an integrative genomics approach to identify all of these proteins and their functions and to understand how their mutated vers...
متن کاملTaking the inventory inside single cells.
developed to measure cell-to-cell differences have typically been based on microscopic imaging of fluorescent proteins 1 or RNA 2,3. These techniques make it possible to monitor RNA or protein fluctuations both in single cells over time and across the cell population , and they are even capable of visualizing single molecules in single cells 4,5. However, they can only be used to monitor a few ...
متن کاملThe prodigious halo of the other Huygens.
At the height of the ceremony in the Principality of Orange of the restoration of the sovereignty of the House of Nassau in 1665, a ceremony led by Christiaan's father, Constantijn Huygens, a "solar crown" appeared in the sky, apparently a divine sign of approval. A nearly forgotten contemporary color engraving of this miraculous event has survived. Constantijn seized the opportunity by using t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science
سال: 1964
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.143.3611.1127